Puromycin

Powder

Puromycin is a selection antibiotic that inhibits protein synthesis in prokaryotes and eukaryotes. Transformed cells containing the puromycin N-acetyl-transferase gene (pac) can be selected.

 Product Code

D919-100MG

 Volume

100 mg

 Storage

+2 °C to +8 °C

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Description

Puromycin is an aminonucleoside antibiotic used for selection of mammalian cell lines expressing the puromycin resistance gene. The antibiotic is active against gram-positive bacteria and various animal and insect cells by inhibiting the peptidyl transfer on prokaryotic and eukaryotic ribosomes. Transfected cells become resistant to puromycin by expression of the pac gene encoding a puromycin N-acetyl transferase.

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